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Native protein mass spectrometry of nuclear receptor-ligand and enzyme-substrate complexes
(2004-11-05)
Nuclear receptors (NRs) are transcription factors that are activated by the binding of low molecular weight ligands. The NR superfamily includes receptors for steroid hormones, anti-inflammatory and lipid-lowering drugs ...
Trends in population health in an era of increasing longevity
(2022-01-26)
In Sweden, the number of older adults over the age of 85 increased by 75% since 1990 while the number of centenarians has almost quadrupled. Rapid population ageing is a global phenomenon and projected to continue in almost ...
Revealing the secrets of MARCO : a target for cancer immunotherapy
(2019-11-06)
Our immune system protects us from infectious agents and sustains the homeostasis in our body. However, the immune system can also play a role in initiation and progression of diseases such as autoimmune diseases and cancer. ...