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Standardization and application of quantitative PCR methods in patients with hematological malignancies
(2004-10-29)
Using modem combination chemotherapy regimens, it has been possible to increase the rate of complete remission (CR) in acute lymphoblastic (ALL) and acute myeloid leukemia (AML). The major reason for treatment failure in ...
Renal function and renal histopathology in assessment of course and prognosis in Henoch Schönlein nephritis and IgA nephropathy
(2011-08-31)
Background: Henoch Schönlein Nephritis (HSN) is a common childhood vasculitis that generally
has a self-limiting course but the long-term outcome varies with the clinical picture at onset.
Morbidity is high among the ...
Molecular specificities of NK cell-mediated recognition of human tumor cells
(2010-01-22)
Natural killer (NK) cells have been implicated in tumor immune surveillance and can reject transformed cells expressing ligands for activating NK cell receptors and low levels of HLA class I. Although NK cells are well ...
The role of proprotein convertases in vascular disease
(2022-10-18)
To date, the role of the proprotein convertase subtilisin/kexin (PCSK) family in vascular disease is largely unknown, with the exception of PCSK9 and its key function in lipid metabolism. The PCSK family constitutes of 9 ...