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Clinically important mycobacteria in Guinea-Bissau, West Africa : phenotypic and genetic diversity
(2004-09-24)
Tuberculosis (TB) is a major and still increasing health problem in West
Africa. In Guinea-Bissau, TB has an estimated annual incidence of
1501100.000. Knowledge on infections caused by nontuberculous
mycobacteria, such ...
Activation of retrovirus spikes for membrane fusion
(2011-05-23)
Retroviruses are enveloped viruses that use reverse transcriptase to convert their RNA genome into DNA which is integrated into the host DNA. They enter into the cell by a membrane fusion process. In this the viral membrane ...
Coagulation during and after cardiopulmonary bypass with focus on heparin, protamine, aprotinin and platelet function
(2019-05-10)
Background: Heparin and protamine dosing for anticoagulation during cardiopulmonary bypass (CPB) and its reversal after CPB, respectively, is usually given according to body weight. Excess protamine may impair coagulation. ...
Interplay of chromatin remodeling, transcriptional regulation, and nuclear organization
(2015-05-12)
Transcription is regulated on different levels to ensure that genes are expressed at the correct time and in the amounts required. At the chromatin level, DNA is wound onto histone proteins, forming nucleosomes that influence ...