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Thioredoxin reductase and selenium in carcinogenesis and multidrug resistance
(2004-05-21)
The thioredoxin system, comprising thioredoxin, thioredoxin reductase (TrxR) and NADPH, is a redox system of great importance in the defence against oxidative stress and is involved in the regulation of several cellular ...
Colon cancer : management and outcome in a Swedish population
(2007-03-02)
Colon cancer is common in Sweden, with about 3500 new cases every year. Tumours of the colon and rectum are usually addressed as an entity. Great effort has been made to improve the outcome after rectal cancer treatment ...
Nutrition, energy metabolism and body composition in the frail elderly
(2006-12-20)
During aging a reduction of energy metabolism, energy intake and fat free
mass can be seen. Some elderly patients experience more pronounced body
weight loss that may lead to malnutrition states. The reasons for the
unintentional ...
Optimization of TB/HIV co-treatment in Ethiopian patients
(2015-11-20)
Tuberculosis (TB) and HIV infection act with deadly synergy. HIV is the most important
risk factor for latent TB reactivation and active TB progression following exposure or
reinfection while TB accelerates HIV progression. ...
Anaemia, blood loss and colorectal cancer
(2015-11-02)
Introduction: Colorectal cancer (CRC) is the fourth most common cancer worldwide and strikes
both sexes. The age-adjusted 5-year survival in Sweden was 60% in the early 21 st century.
Approximately 50% of patients are ...
Emergency care seeking behaviour : in relation to patients' and providers' perceptions and attitudes
(2010-10-29)
Background: This study was developed with the main objective of evaluating users of
emergency departments (ED) triaged as non-urgent following a period of time when large
cutbacks in hospital and ambulatory care were ...
Aspects on local recurrence of rectal cancer
(2009-04-09)
Rectal cancer is a common malignant disease in Sweden which is diagnosed in about 1,800 patients annually. Local failure, defined as residual or recurrent disease within the pelvis, is of major concern in rectal cancer ...
Progressive elements in type 2 diabetes, studies on secondary failure and diabetic complications
(2008-12-26)
Diabetes is a progressive disease with late complications, one of the most common being diabetic neuropathy (DN). DN can lead to serious complications and accounts for more hospitalization and higher costs than all other ...
Cardiovascular assessment in middle-aged male long distance runners
(2012-11-21)
Endurance events such as long distance running races are increasing in popularity and convey multiple health benefits. However, such exercise forms also represent a major challenge to human cardiovascular physiology and ...
Akt signaling and coordinated changes in the distribution and expression of Akt-regulating phosphatases
(2014-04-30)
Cancer is one of the major causes of death worldwide. The PI3K/Akt signaling pathway is up-regulated in a variety of human cancers. Akt is an important signaling molecule in cellular survival pathways. Activated Akt (pAkt) ...