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Preclinical studies of ribozyme-mediated gene therapy for HIV-1
(2004-05-14)
Approximately 40 million people are infected with HIV-1 and AIDS is the number one cause of death in Africa as well as, the fourth leading cause of death globally. Patients in developed countries generally receive highly ...
Studies on the hormonal regulation of bile acid synthesis
(2007-01-05)
The maintenance of a normal turnover of cholesterol is of vital
importance, and disturbances of cholesterol metabolism may result in
several important disease conditions. The major route for the elimination
of cholesterol ...
Pituitary regulation of plasma lipoprotein metabolism and intestinal cholesterol absorption
(2005-11-18)
Increased levels of plasma cholesterol are associated with a higher risk to develop atherosclerosis, the leading cause of death in Western societies. The major part of cholesterol in human blood is transported within ...
Studies on the effects of thyroid hormone on cholesterol and lipoprotein metabolism
(2012-11-22)
Elevated plasma lipids, particularly cholesterol within low density lipoproteins, is an important risk factor for developing atherosclerosis which can cause angina pectoris, myocardial infarction, and stroke. Thyroid hormone ...
Studies on cholesterol and lipoprotein metabolism : emphasis on diabetes and sugar
(2015-05-08)
Cholesterol has important functions in the body; as a precursor in the synthesis of steroid hormones and bile acids (BAs), and as a component of cellular membranes. However, an elevated level of plasma cholesterol, transported ...
Targeting MYC and CDK2 in cancer : impacts on senescence, apoptosis and immune modulation
(2021-05-27)
Cancer is a disease in which cells acquire the ability to divide uncontrollably and invade other tissues. An important component of this process is the activation of oncogenes and inactivation of tumor suppressor genes. ...