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Brain control of energy balance : localization and regulation of proteins involved in the central control of food intake and body weight
(2004-02-20)
Obesity has become a worldwide threat to human well-being and is now so
common that it is beginning to replace undernutrition and infectious
disease as the most significant contributor to ill health. Obesity
increases ...
DNA methylation and 5-azacytidine in myelodysplastic syndromes : pharmacodynamic, mechanistic and clinical studies
(2007-11-26)
Promoter DNA hypermethylation and hence silencing of e.g. tumour
suppressor genes is considered to be an important step in carcinogenesis
and has been associated with poor outcome in patients with
myelodysplastic syndromes ...
Hysterectomy on benign indications and pelvic floor dysfunction : clinical and epidemiological aspects
(2010-01-29)
The objectives of this thesis were to investigate the annual rates for
hysterectomy on benign indications, to evaluate the effects of
hysterectomy on bowel function, to identify risk factors for vaginal
vault prolapse, ...
Interactions between neuroblastoma and the immune system : cellular pathways and mediators
(2011-03-04)
Neuroblastoma (NB) is an embryonal tumor of early childhood arising in tissues of the sympathetic nervous system, such as the adrenal gland and paraspinal ganglia. It is the most common extra-cranial solid tumor of childhood, ...
Parents who have lost a son or daughter through suicide : towards improved care and restored psychological health
(2013-12-19)
Background: Parents that have lost a son or daughter through suicide are at risk of developing psychological morbidity that may become long-lasting and even life-threatening. Despite this the aftermath of a suicidal loss ...