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Bronchoalveolar lavage and serum protein patterns in healthy individuals and sarcoidosis patients : a proteomics approach
(2004-01-23)
The etiology of sarcoidosis remains unknown. Although biochemical changes
are frequently observed in sarcoidosis, the problem of finding distinct
biomarkers remains. Only a few markers are defined in this disease. ...
Analyses of protein evolution, function, and architecture
(2010-01-25)
Proteins can evolve over time in many different ways. An ancestral protein sequence inherited in different species will gradually undergo changes in primary sequence and sometimes in domain architecture. Some of these ...
Regulation of Hedgehog signalling during development and carcinogenesis
(2009-11-26)
Hedgehog (Hh) signalling is one of the most important signalling networks in the body and, when miss-regulated, has been implicated in many human tumours, particularly that of skin (Basal Cell Carcinoma, BCC) and brain ...
‛The virus stops with me’ : couples living positively with HIV in rural, eastern Uganda
(2012-09-21)
Background: Historically people living with HIV (PLHIV) were left out of the center of the HIV prevention agenda in Africa, yet more recently greater attention has been placed on interventions that forefront PLHIV.
Aim: ...
Prognostic and biological implications of epigenetic changes in leukemia
(2011-12-23)
The field of epigenetic research in hematology and oncology is rapidly expanding. Even so, reliable data linking epigenetic changes to clinical outcomes are scarce.
We conducted two retrospective studies in AML. The ...