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Natural and induced immunity against the tumour-associated antigen, Ep-CAM
(2003-11-27)
The tumour-associated antigen (TAA), Ep-CAM is overexpressed on various human carcinomas, including colorectal carcinoma (CRC). TAAs or their immunodominant epitopes that are spontaneously recognised by the immune system ...
Autoimmune markers in autoimmune diabetes
(2003-12-19)
Type 1 diabetes mellitus (T1DM) is an autoimmune disease, characterized by autoimmune mediated loss of insulin secreting Beta-cells. The disease is associated with certain HLA class 11 haplotypes. HLA DR3-DQ2 and DR4-DQ8 ...
Primary deep vein thrombosis in an upper limb : a retrospective study with an emphasis on the pathogenesis and late sequelae
(2016-11-04)
Background: Upper extremity deep vein thrombosis (UEDVT) is an uncommon disease with an incidence of 1–11% of all deep vein thrombosis. UEDVT can be classified into two groups, primary and secondary UEDVT. Primary UEDVT ...
To kill two birds with one stone : targeting myeloid cells in cancers
(2015-05-08)
Cancer progression is often accompanied by chronic inflammation and severe impairment of the immune system. In recent years, therapies eliciting tumor-specific immunity have resulted in striking tumor control and survival ...