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Immunopathogenesis of Guillain-Barré syndrome and chronic inflammatory demyelinating polyradoculoneuropathy
(2002-11-15)
Guillain-Barre syndrome (GBS) is an inflammatory polyradiculoneuropathy with acute onset and usually a spontaneous recovery. Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a chronic progressive ...
A study of b-secretase cleaved Alzheimer amyloid precursor protein
(2002-04-05)
Alzheimer's disease (AD) is characterized by the degeneration and loss of neurons, intracellular neurofibrillary tangles and the accumulation of extracellular senile plaques consisting mainly of beta-amyloid (A-beta). ...
Studies of nuclear encoded mitochondrial proteins in metabolism
(2021-11-19)
Mitochondrial function is vital for human health. Inherited genetic disease can cause mitochondrial DNA (mtDNA) deficiency, disorders with generally poor prognosis. The majority of the genesinvolved in keeping a normal ...
Twin-twin transfusion syndrome (TTTS) : outcomes with special reference to cardiovascular function
(2013-05-02)
Background: Fetal environment has become a subject for increasing interest when studying health and disease in adults. Monozygous (MZ) twins, especially gestations complicated with twin-twin transfusion syndrome (TTTS), ...
The risk of type 1 diabetes in immigrants and their offspring in Sweden : the influence of perinatal factors
(2014-11-13)
Aims: The overall aim of this study was to investigate the trend in and risk factors for type 1 diabetes, with particular reference to parental socioeconomic position (SEP) and country of birth of subjects and their parents. ...
Idiopathic scoliosis : aspects on surgical and non-surgical treatment
(2023-01-23)
The term scoliosis has been used to describe conditions that lead to deformation of the spine. It derives from the ancient Greek ‘σκολίωσις’ and the root word ‘σκολιός’ which means ‘bent or crooked’. In its most common ...
Genetic variability commonly affecting neurodegeneration and neuroinflammation
(2012-05-10)
Loss of nerve cells and axons is a common feature of common complex neurodegenerative disorders, such as Alzheimer’s and Parkinson’s diseases. However, also Multiple Sclerosis (MS), primarily an autoimmune disorder, has a ...
A clinical study of uncemented hip arthroplasty : radiological findings of host-bone reaction to the stem
(2006-02-24)
In total hip arthroplasty (THA), the main reason for failure leading to revision is aseptic loosening. Both mechanical and biological effects act in the loosening process, the factors may be implant design, fixation mode ...
Immune mechanisms in atherosclerotic vascular disease
(2002-05-14)
Atherosclerosis has been categorized as an inflammatory disorder, with similar chronic inflammatory conditions found in rheumatoid arthritis. It entails an unregulated accumulation of lipids in the vessel wall, which leads ...
Health outcomes of women with breast cancer
(2014-12-17)
The overall survival of breast cancer patients has increased quite remarkably in the past decades in the developed countries due to substantial improvements in diagnosis and treatment. As a consequence, the proportion of ...