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Transcriptional mechanisms directing terminal differentiation of B lineage cells
(2002-11-01)
The interaction between the B cell receptor (surface immunoglobulin) and
its ligand (antigen) can result in extensive cell growth and induction of
differentiation. The terminally differentiated B cell fulfills the
ultimate ...
Serine / threonine protein phosphatase 5 – a double-edged sword : in the progression towards diabetes
(2012-05-15)
Type 2 diabetes mellitus is increasing at an alarming rate worldwide. In the development and progression of type 2 diabetes mellitus, the insulin-producing pancreatic β-cells are commonly exposed to a hyperglycemic and ...
Sentinel lymph node biopsy in breast cancer : aspects on indications and limitations
(2017-03-29)
Axillary lymph node status is the most important prognostic factor in breast cancer. Sentinel lymph node biopsy (SLNB) was introduced in the late 1990s and has replaced axillary lymph node dissection (ALND) as the gold ...