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Humoral immunity to recombinant human autoantigens in organ-specific autoimmune disease
(1996-05-29)
Insulin-dependent diabetes mellitus (IDDM) and idiopathic Addison's disease are organ-specific autoimmune diseases characterized by the presence of circulating autoantibodies. The role of autoantibodies in the pathogenesis ...
New approaches to preparation and storage of platelets
(2012-10-26)
During the last century, transfusion of blood components has become a prerequisite for treatment in many clinical settings. The availability of plastic bags and methods for centrifugation and separation of blood cells, has ...
Decoding the contribution of transcription factors to cell fate determination
(2018-11-19)
It is well accepted that transcription factors (TFs) play a crucial role in determining cell identity. Although RNA expression or protein abundance data show that a large fraction of the total TFs are expressed in a given ...