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Gene mapping of atopic dermatitis
(2001-11-14)
Atopic dermatitis is a hereditary, pruritic, inflammatory and chronic skin disease that typically presents in early childhood. It is often associated with other atopic manifestations, such as asthma, allergic rhinoconjunctivitis, ...
The treatment of depression in clinical practice : a public health perspective
(2004-05-14)
Depression is a major public health problem with a reported point prevalence of 5%. Depressive illness causes great suffering and disability. Effective treatment with antidepressant drugs has been available for more than ...
Trinucleotide repeats and neuropsychiatric phenotypes
(2001-11-02)
Genetic studies of affective disorders have yielded several chromosomal regions suggestive for linkage. Linkage analysis was performed in five families with unipolar affective disorder, collected from northern Sweden. Four ...
Body and soul : studies on health and psychosomatic complaints among adolescents in Sweden
(2008-10-07)
Objective: The aim of this thesis is to describe the health of the
adolescents with special emphasis on psychosomatic complaints.
Method: Both quantitative and qualitative methods were used to get a
insight into ...
Dissection of HIV-1 Env-specific B cell responses in non-human primates
(2010-04-27)
It has been almost 30 years since the identification of HIV as the causative agent of AIDS. Despite considerable efforts to halt the spread of the virus, the epidemic continues in many parts of the world. The most efficient ...
Chronic immune activation and lymphocyte apoptosis during HIV-1 infection
(2012-01-26)
HIV-1 infected individuals are subject to a chronic immune activation resulting from HIV-1 replication, microbial translocation, and lymphopenia. Despite the great advance of antiretroviral treatment (ART), the immune ...
Impairment of B cell trafficking and differentiation during HIV-1 infection
(2011-10-05)
During the course of HIV-1 infection, several B cell dysfunctions occur as result of virus replication and indirect mechanisms of immunopathology. The B cells abnormalities include hypergammaglobulinemia, a decreased number ...
Single cell studies of human T cell function with applications for HIV-1
(2016-04-18)
T cells are one of the body’s main defenses against viruses and cancers and are therefore considered to play a major role in immunotherapies after stem cell transplantation and in HIV-1 vaccine and cure strategies. However, ...
On antidepressant effects of running and SSRI : focus on hippocampus and striatal dopamine pathways
(2007-05-25)
Considering the heterogeneous character of depression, it seems likely
that many brain regions are involved mediating the diverse symptoms of
depression. For example, the mesolimbic DA system has a central function
for ...
Tissue prostatic specific antigen (T-PSA) : a way to predict and understand the development of prostate cancer
(2001-09-21)
Prostate cancer (CaP) is the most prevalent malignancy among men in
Sweden. One major problem associated with CaP is the choice of treatment
since the disease may develop very differently from patient to patient.
Many ...