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Exercise effects on the mitogen-activated protein (MAP) kinase cascade in skeletal muscle
(2000-11-03)
Exercise-induced adaptations in skeletal muscle are regulated by numerous signaling mechanisms. However, little is known about the molecular signaling mechanisms linking muscle contraction or other exercise-associated ...
Effects of endocrine disruptors on adreno-cortical and Leydig cell steroidogenesis
(2007-08-24)
A common sequential pathway for steroidogenesis, designed to produce steroid hormones, is expressed in the adrenal cortex, testes and ovaries. In this process, cholesterol is converted to all known steroids by specific ...
Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors
(Springer Nature, 2022-08-02)
Heart regeneration is an unmet clinical need, hampered by limited renewal of adult cardiomyocytes and fibrotic scarring. Pluripotent stem cell-based strategies are emerging, but unravelling cellular dynamics of host–graft ...