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Deoxyribonucleoside kinases in nuclear and mitochondrial DNA precursor synthesis : phosphorylation of anti-cancer nucleoside analogs in different subcellular compartments
(2000-09-12)
Nucleoside analogs have been developed as anticancer and antiviral agents. The main mechanism of action of nucleoside analogs is the incorporation of the corresponding analog triphosphate into DNA where it interferes with ...
Post-translational and therapy-induced modifications in rheumatoid arthritis
(2008-05-09)
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial proliferation and excessive mononuclear infiltration leading to destruction of bone and cartilage, with subsequent joint deformities and ...
Clinical and epidemiological project in cancer-associated dermatomyositis : the role of anti-TIF1γ antibodies
(2023-01-27)
Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of rare chronic autoimmune inflammatory diseases causing a debilitating muscle weakness but encountering even other symptoms such as arthritis, skin rash, ...
Health care on equal terms for immigrants in Sweden
(2012-08-24)
Background: There is limited knowledge about immigrant patients’ lower self-reported health (SRH) in relation to acculturation and discrimination and about immigrant patients’, interpreters’ and GPs’ experiences, reflections, ...