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Trophic factors, neuroprotection and spinal cord repair
(2000-09-01)
Background: There is no cure for paralysis. The only drug therapy presently in use, acute high-dose methylprednisolone, has only modest effects on outcome. There is therefore a great need for new therapies. Trophic factors, ...
Genetic association studies of symptoms, comorbidity and outcome in bipolar disorder and schizophrenia
(2016-05-06)
Schizophrenia and bipolar disorder are complex brain disorders. Research has focused on
applying brain research to understand the etiology, as well as clinical research to improve
treatment, prognosis and progression. ...
Molecular epidemiology of complex heritable disease : applications in genomics and metabolomics
(2012-12-21)
Modern high-throughput molecular technologies (collectively referred to as “omic” platforms) are generating unprecedented amounts of data on human variation. The four papers in this thesis each investigate and characterize ...
Bleeding in abdominal aortic aneurysm repair
(2015-05-06)
Background and aims: Massive bleeding in open abdominal aortic aneurysm (AAA) repair is associated with worse outcome. However, few studies have investigated specific problems related to perioperative bleeding and blood ...
Strategies for modulation of dendritic cell responses
(2012-05-10)
With increased knowledge in dendritic cell (DC) biology, innate immune receptors and their ligands, and the shaping of adaptive responses, refined approaches to modulate our immune system are today emerging as treatment ...
Inflammation as a therapeutic target for Alzheimer's disease
(2010-04-02)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder
which is characterised by impairment of memory and learning. The
impairment is caused by neuronal death which originates in the parts of
the brain ...