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5-HT receptor-mediated modulation of glutamate transmission in the hippocampus and prefrontal cortex and its relation to cognition and depression
(2014-09-24)
Depression is a multifaceted disease which is marked by cognitive and emotional memory impairments. It is characterised by an imbalacement of serotonergic and glutamatergic system in brain areas such as hippocampus and ...
Anti-TNF therapy and malignancy in patients with rheumatoid arthritis : studies on cancer incidence, recurrence and survival
(2014-08-29)
Tumor necrosis factor i nhibitors (TNFi) h ave become a backbone treatment of rheumatoid arthritis (RA). TNF has multiple and incompletely understood functions in tumor biology, and cancer is considered a potential adverse ...
Infection early in life and risk of non-affective psychosis
(2015-04-07)
In light of the increasing, but insufficient, evidence that various infections and immunological processes during brain development are associated with psychotic disorder, the aim of this thesis was to investigate infection ...