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Targeted therapy and outcome in chronic lymphocytic leukemia
(2014-11-03)
Despite major advances, chronic lymphocytic leukemia (CLL) is still considered incurable. Fludarabine refractory patients and those with TP53disruptions have a particularly poor prognosis. Alemtuzumab is an established ...
Neuropathic pain in an elderly population of an urban area of Iran with a special focus on carpal tunnel syndrome : epidemiological aspects, clinical characteristics, and non-surgical therapy
(2022-01-14)
Background: People are getting older, and aging problems and disorders are increasing fast. Knowing the rates, causes, symptomatology, treatment, relief, and prognosis of associated disorders can help and facilitate the ...
Characterizing cancer cell signaling at the protein level : from targeted to proteome and phosphoproteome‐wide analyses
(2017-09-11)
Proteins are the effectors of cellular functions and the constituting elements of cellular signaling cascades. The ability to analyze the abundances and the dynamics of proteins is central to dissect cellular signaling and ...