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Visuo-thermal congruency modulates the sense of body ownership
(Springer Nature, 2022-09-08)
Thermosensation has been redefined as an interoceptive modality that provides information about the homeostatic state of the body. However, the contribution of thermosensory signals to the sense of body ownership remains ...
Visual perception in infancy and its links to later autism
(2024-01-24)
Alterations in primary sensory areas of the brain have been suggested to be at the roots of the well-documented visual perceptual differences in autism. However, despite the possible key role these sensory processing ...
Hepatic diseases at the molecular level : identifying novel targets and biomarkers through transcriptomics
(2024-05-03)
In the last few decades, the prevalence of obesity and metabolic diseases have dramatically increased and pose a major threat to global healthcare systems. The chronic excess of carbohydrates and fat is a risk factor for ...
Immunometabolic reprogramming during suppressive HIV-1 infection
(2022-05-10)
Since the implementation of antiretroviral therapy (ART), infection with human immunodeficiency virus type-1 (HIV-1) has been transformed into a chronic lifelong condition. The main obstacle for a HIV-1 cure is the persistence ...
Characterizing and exploiting the endocytic pathway for macromulecular delivery
(2022-04-29)
Macromolecular drugs with cytosolic or nuclear targets often exhibit low therapeutic activity due, at least in part, to their inability to escape endosomal compartments following cellular internalization. There exist a ...
Perks and considerations when targeting functional non-coding regions with CRISPR/Cas9
(2023-05-12)
Since the CRISPR system was discovered as an adaptive immune response in prokaryotic cells, the past decade has witnessed the engineering and deployment of CRISPR/Cas9 as one of the most efficient and powerful molecular ...
Degradation and sequestration : cellular strategies to counteract proteotoxic stress
(2022-10-06)
Maintenance of proteome homeostasis (proteostasis) is essential to preserve cellular function in response to intrinsic and extrinsic stress conditions. This is regulated by the proteostasis network, which is comprised of ...
Maternal obesity and offspring metabolic outcomes : focus on sex differences
(2022-04-01)
Obesity is a worldwide health issue affecting all ages and both sexes, and its prevalence is progressively increasing among adults and children. The predisposition to metabolic complications caused by obesity is sex ...
Expression of prostaglandin E synthase-1 in periodontitis : in vivo and in vitro studies
(2014-05-07)
Periodontitis is a chronic inflammatory disease characterized by destruction of the supporting structures of the teeth, including gingival tissues and alveolar bone. In advanced cases of periodontitis the ultimate clinical ...
Immunometabolic regulation in natural HIV-1 control
(2022-04-28)
The elite controllers (EC) are a rare group of people living with HIV-1 infection (PLHIV) that can control viral replication in the absence of antiretroviral therapy for a prolonged time. The mechanisms behind elite control ...