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Quantifying cancer patient survival : extensions and applications of cure models and life expectancy estimation
(2013-10-18)
Cancer patient survival is the single most important measure of cancer patient care. By quantifying cancer patient survival in different ways further insights can be gained in terms of temporal trends and differences in ...
Aspects of positive and negative mental health in young people, aged 16-29 years : measurements, determinants, and interventions
(2019-08-07)
. First, we investigated if the 12-item General Health Questionnaire (GHQ-12) had the capacity to measure PMH in addition to NMH. We employed data from the cross-sectional Swedish National Public Health Survey 2004-2009, including 41,668 individuals aged...
Novel insulin-like growth factor-binding protein proteases : detection and characterization
(2006-10-07)
Members of the insulin-like growth factor (IGF) system are known to have an impact on cell differentiation, proliferation and survival, and to be important regulators for nutrient metabolism. The IGF-binding proteins ...
Proteolysis of insulin-like growth factor-binding protein-1, -2 and -4 : function of fragments
(2011-12-21)
The insulin-like growth factors (IGF-I and IGF-II) stimulate cell growth, survival and differentiation, and have insulin-like activity. A family of six IGF-binding proteins (IGFBP-1 through -6) bind to IGFs with high ...
Flexible parametric models for cancer patient survival : loss in expectation of life and further developments
(2018-03-01)
Population-based cancer studies can contribute to a better understanding of cancer patient survival. The general aim of this thesis was to develop and apply statistical methods for population-based cancer studies to ensure ...