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Environmental risk factors for autism spectrum disorders
(2013-04-04)
Aims: Two overarching hypotheses were tested in this thesis- first, that the environmental factors studied during pregnancy or the time preceding birth would be associated with a higher risk of autism spectrum disorders ...
Studies on the activation of cytosolic phospholipase A2 and 15-lipoxygenase-1
(2006-11-28)
Arachidonic acid is a polyunsaturated fatty acid, which has four double bonds and belongs to the omega-6 family of fatty acids. Even if it can be formed in humans from one essential fatty acid, the linoleic acid, most of ...
Studies on the activation of cytosolic phospholipase A2 and 15-lipoxygenase-1 in hematopoietic cells
(2009-04-08)
Arachidonic acid is a polyunsaturated fatty acid that has four double bonds and belongs to the omega-6 family of fatty acids. Although it can be formed in humans from one essential fatty acid (linoleic acid), most of the ...
Leukotrienes and leukotriene receptors : potential roles in cardiovascular diseases
(2007-01-01)
Leukotrienes (LTs) are a family of lipid mediators that are involved in
host defense and inflammatory responses. They are synthesized from
arachidonic acid through the 5-lipoxygenase (5-LO) pathway, and are
divided into ...
Resolving inflammation : analysis of mechanisms in relation to Alzheimer pathology and aging
(2021-08-10)
Alzheimer’s disease (AD) is the most common type of dementia, and its clinical symptoms are the reflections of pathological changes in the brain. The main pathological features of AD are intracellular aggregates of ...