Search
Now showing items 1-3 of 3
Insulin-like growth factor-I deficiency, insulin sensitivity, and glucose metabolism
(2013-02-20)
In children and adolescents, growth hormone (GH) and insulin-like growth factor-I (IGF-I) act in concert to stimulate linear growth; however, the effects on glucose metabolism are in opposition. GH increases insulin ...
Fission yeast mediator complex and its role in transcriptional regulation
(2011-03-01)
Mediator is an evolutionary conserved co-activator complex that regulates transcription of protein encoding genes in eukaryotes. This multiprotein complex was first identified in budding yeast and shown to be indispensable ...
Conserved structure-function relationships in the mediator complex
(2007-02-16)
The Mediator complex is an essential multiprotein coregulator of RNA polymerase II (pol II)- dependent transcription in fungi and metazoans. Mediator interacts directly with both pol II and sequence-specific transcriptional ...