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Genetic predispositions to rheumatoid arthritis in Malaysian population
(2012-11-15)
Genetic predisposition is a significant and fundamental determinant of susceptibility to rheumatoid arthritis (RA), a complex autoimmune disease with a painful and disabling condition. The vast majority of genetic studies ...
11beta-Hydroxysteroid dehydrogenase type 1 as a pharmacological target in metabolic disease
(2004-04-08)
The metabolic syndrome is a collection of associated disorders, affected by lifestyle, genetic predisposition and environment, and emerges as a consequence of the Western society lifestyle. It describes a variety of ...
Novel pharmaceutical approaches to regulate glucose homeostasis
(2010-01-13)
The Western sedentary life-style and calorie excess is causing an increased incidence of obesity and type 2 diabetes. When untreated, these diseases are associated with heart- and vascular disease, stroke, cancer, neuropathic ...
Empty glasses and broken bones : epidemiological studies on alcohol and injuries treated at an emergency department in Switzerland
(2009-03-06)
Background: Injury-related deaths and Disability-Adjusted Life Year
(DALY) represent an important share of the burden of disease worldwide.
Acute prior-to-injury alcohol consumption is a known risk factor for
injuries. ...