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Chromatin remodelers and their roles in chromatin organization
(2012-11-20)
The DNA in the eukaryotic nucleus is organized into a complex DNA-protein structure called chromatin. The basic repeating unit of chromatin is the nucleosome, which consists of 147 bp of DNA wrapped around a histone protein ...
Tissue microbiology : an integrated approach for intravital studies of host-pathogen interactions
(2017-05-08)
A bacteria infection in the living host is the summation of a myriad of interactions. Reductionistic and sacrificial experiment models cannot replicate this complexity. The Tissue Microbiology approach overcomes this by ...
The dynamics of intra- and inter-organ communication during an acute kidney infection
(2022-01-27)
This thesis focuses on the roles of neuro-immune communication and infection-mediated coagulation during bacterial kidney infections. We demonstrate dynamic intra- and inter-organ host responses, where the outcome of an ...