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Dissection of HIV-1 Env-specific B cell responses in nonhuman primates
(2012-10-25)
Vaccine-induced protection is generally mediated by long-lived antigen-specific B cell responses. Most licensed vaccines target pathogens that display relatively low variability, but for highly variable pathogens, such as ...
Inheritance of autoimmune neuroinflammation
(2010-04-02)
Multiple sclerosis (MS) is a chronic neuro-inflammatory disease with anticipated complex etiology. Susceptibility to MS is conferred by numerous genes, with very low odds ratios that explain minute fractions of disease. ...
Health effects of snus use : cardiovascular diseases, weight gain and obesity
(2012-11-08)
Use of snus is most prevalent in Nordic countries, and especially in Sweden, where 18% of men and 3% of women are daily users. Snus is also used to a minor extent in the United States where an increasing interest is seen ...
Treatment of uncomplicated malaria in Guinea-Bissau
(2006-03-10)
Treatment of malaria has become increasingly difficult due to high levels of resistance to the cheap and commonly used antimalarials. In Guinea-Bissau, the first line drug is chloroquine (CQ), the second line drug is ...
Recurrent low-back pain : exercise intervention and predictive factors
(2009-04-03)
Low-back pain continues to be one of the main problems for which subjects
seek treatment in primary care. While the natural history of low-back
pain is often considered to be good, many sufferers get further episodes
that ...
Targeting of the Myc pathway as a novel approach for cancer therapy
(2006-11-24)
As transcription factors, Myc-family proteins function upstream of signaling pathways and regulate cell proliferation, differentiation, angiogenesis, apoptosis and transformation. Precisely regulated Myc expression is ...