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Assessing infection risk and evaluating prevention strategies in the era of HPV-vaccines
(2012-10-15)
Aim: This thesis aims to provide a multidimensional assessment of infection risks and to evaluate strategies for HPV prevention including vaccination with quadrivalent HPV-vaccines, dose-level vaccine effectiveness and ...
Novel properties of mature adipocytes in obesity and hyperinsulinemia
(2020-02-10)
Adipose tissue expansion and dysfunction, which leads to obesity and related metabolic diseases (e.g., diabetes and hypertension) are currently the most costly challenges for public health, yet the mechanisms underlying ...
Neuroblastoma as a target for effector mechanisms of the immune system
(2007-05-24)
Neuroblastoma (NB) is the most common solid extracranial tumor in
children. Despite intensive multimodal treatment, the prognosis for
high-risk NB patients remains poor and therefore new treatment modalities
are needed. ...
Interactions between neuroblastoma and the immune system : cellular pathways and mediators
(2011-03-04)
Neuroblastoma (NB) is an embryonal tumor of early childhood arising in tissues of the sympathetic nervous system, such as the adrenal gland and paraspinal ganglia. It is the most common extra-cranial solid tumor of childhood, ...