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PCR and sequencing based methods for detection and typing of pathogenic microorganisms
(2011-11-18)
The potential use of bacteria and viruses as biological terror weapons makes certain highly pathogenic microorganisms a worldwide public health threat. In an outbreak investigation involving a possible deliberate spread ...
An experimental study of mediators in allergic bronchoconstriction with focus on eicosanoids
(2008-02-01)
Mast cells have a central role in the inflammatory response in airways of both atopic and non-atopic asthmatics. The mast cell-derived mediators such as histamine, leukotriene C4 and prostaglandin D2, released upon activation ...
Genetic variability commonly affecting neurodegeneration and neuroinflammation
(2012-05-10)
Loss of nerve cells and axons is a common feature of common complex neurodegenerative disorders, such as Alzheimer’s and Parkinson’s diseases. However, also Multiple Sclerosis (MS), primarily an autoimmune disorder, has a ...
Apoptosis, cellular division or mitotic catastrophe? Effects of kinase inhibition and DNa damage in lung cancer cells
(2007-01-07)
Non-small cell lung cancer (NSCLC) cells are generally characterized by a
low response to conventional anti-cancer agents, such as DNA-damaging
drugs. Treatments that induce DNA damage relies on cellular signalling
resulting ...
Risk factors and outcomes in inflammatory myopathies
(2023-05-04)
Idiopathic inflammatory myopathies (IIM) are complex autoimmune diseases associated with high morbidity and mortality. Although knowledge about the pathogenic mechanisms underlying IIM is improving, limited data are available ...
Terminology systems for health problems and procedures in primary care
(2011-09-20)
Background and overall aim: Semantic interoperability addresses issues of how to best facilitate the coding, transmission and use of meaning across seamless health services, between providers, patients, citizens and ...