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Regulation of Plasmodium falciparum virulence genes and immune response to surface antigens in placental malaria
(2011-11-15)
Malaria infection caused by the parasite Plasmodium falciparum is a deadly torment, especially for young children and pregnant women residing in sub-Saharan Africa. Much of the parasites virulence is due to its ability to ...
In search of diagnostic and prognostic markers for thyroid cancer : a proteomics approach
(2010-04-09)
Early diagnosis of cancer can influence the therapeutic strategy
increasing the chances of cure or, at least, prolonged survival. It is
equally important to be able to detect prognostic signs, i.e. tumor
features that ...
Studies on antioxidant and lipid lowering effects on human microcirculation
(2002-10-18)
In previous work from this laboratory, vital microscopy was successfully
used to study rnicrocirculatcry effects of hypercholesterolemia in a
rabbit model. Hypercholesterolemia caused a dramatic depression of the
blood ...
Nucleoside analog toxicity and nucleoside kinase deficiency : effects on mitochondrial DNA
(2008-09-05)
Nucleoside analogs are modified nucleosides used in treatment of cancer
and viral infections. They are dependent on intracellular phosphorylation
to be pharmacologically active. Deoxyribonucleoside kinases catalyze ...
Glossopharyngeal breathing
(2008-03-21)
Introduction and aims: The technique of glossopharyngeal breathing was introduced already in the 1950 s, but today, few health professionals are aware of its uses. The technique is performed by using the glossopharyngeal ...
Ligand-induced structural changes in HIV-1 envelope glycoprotein
(2013-09-02)
The first step in HIV-1 entry is the interaction between viral envelope glycoprotein gp120 and CD4 receptor on permissive host cells. The interaction initiates a series of sequential conformational rearrangements that ...
Urinary steroid profiles in doping testing : in relation to natural variation and drug administration
(2018-03-02)
To detect doping with endogenous steroids, such as testosterone, biomarkers in urine are measured. These biomarkers include testosterone and some metabolically related steroids. The measured steroids are combined into ...
Prognostic factors for whiplash associated disorders
(2020-02-21)
Disability and chronic pain secondary to low- speed vehicle collisions has been a known condition since the nineteenth century. Today, whiplash-associated disorders (WAD) are the most common personal injuries reported to ...
Managing children with pneumonia symptoms in malaria endemic Uganda
(2008-12-23)
Background: Pneumonia is one of the leading killers of children under
five years of age. In sub-Saharan Africa, symptoms of pneumonia often
overlap with those of malaria. While many countries have made public
commitments ...
Glycan-based interactions of Streptococcus pneumoniae and the host
(2017-05-17)
Streptococcus pneumoniae is commonly found as an asymptomatic colonizer of the nasopharynx of children, but it can also translocate to normally sterile body sites and cause severe diseases, like pneumonia, septicemia or ...