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Tumor-mediated changes in the immune system of cancer patients : a balancing act between suppressors and effectors
(2011-10-25)
Tumors and immune cells interact in many ways: immune cells can recognize and even kill tumor cells, while the tumor on the other hand can induce cells of the immune system to participate in tumor-mediated immune ...
Studies on the mechanisms of carcinogenesis and cancer cell death
(2013-02-05)
Gastric cancer is the second most common cause of cancer-related mortality in the world. The mechanisms of gastric carcinogenesis are not fully elucidated. Telomerase and its catalytic subunit telomerase reverse transcriptase ...
Human 15-lipoxygenase-1 and telomerase gene expression in cancer and inflammation
(2008-03-07)
Human 15-lipoxygenase type 1 (15-LOX-1) is an enzyme that catalyzes the oxygenation of free or membrane-bond polyunsaturated fatty acids containing at least one bis-allylic methylene moiety. The enzyme has been proposed ...
Vascular function in bicuspid aortic valve disease
(2014-10-31)
The aortic valve normally consists of three cusps (tricuspid aortic valve, TAV), but in
0.5-2% of the population it consists of only two cusps (bicuspid aortic valve, BAV),
which is the most common congenital cardiac ...
Telomerase reverse transcriptase (TERT) : promoter mutation and novel function in human cancer
(2014-05-21)
Telomerase reverse transcriptase (TERT) is the catalytic component of telomerase, an RNAdependent DNA polymerase responsible for telomere elongation. TERT is transcriptionally repressed in most normal human somatic cells ...
Mechanisms of flavor perception : how odor and taste interact when we eat
(2021-06-02)
Every time we eat, our brains are bombarded with sensory information from the olfactory and gustatory modalities. Through a binding process that is not fully understood, the odor and taste are then merged into flavor, a ...