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The impact of vascular structure and function on tumor growth, retinopathy, and antiangiogenic therapy
(2011-08-22)
Tumors produce multiple angiogenic factors to stimulate neovascularization that is essential for tumor growth, invasion and metastasis. Despite the known angiogenic functions of each individual factor, the interplay between ...
Kinetics of protein-based in vivo imaging tracers for positron emission tomography
(2015-11-20)
Within the framework of the “Sel-tag imaging project”, a novel method was used to rapidly label protein tracers and the in vivo targeting abilities of these tracers were studied in animal models of cancer using a preclinical ...
Statistical methods for long-term follow-up of infectious diseases
(2014-02-21)
The overall aim of this work has been to investigate methodological issues connected to long-term follow-up of infections diseases. The work extended to prevalent cohorts in general. The common denominator for the main ...
Avidity-guided radionuclide therapy for thyroid cancer
(2022-09-01)
The treatment of differentiated thyroid cancer has three main modalities: surgery, hormone suppression and radioiodine therapy. Effective radioiodine therapy requires cancer cells to be iodine avid, i.e. exhibit relatively ...
Development of radiometal-based labelling techniques and tracers for non-invasive molecular imaging
(2022-03-03)
Metallic radionuclides, radiometals, have an important role in nuclear medicine. Their straightforward coordination radiochemistry allows for a large variety of applications. The similarities and differences between the ...