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Calcium signaling in development and disease
(2011-01-13)
The calcium ion (Ca2+) is a highly versatile signaling messenger involved in a diverse range of physiological processes such as gene transcription/expression, proliferation, differentiation and cell death. Intracellular ...
Acute pesticide poisonings in Nicaragua : underreporting, incidence and determinants
(2009-11-24)
Background: Acute pesticide poisonings (APP) are a public health problem in Nicaragua. The quality and coverage of APP´s register, the real incidence of APP, the main determinants, the economic cost of treating cases and ...
Interferons in antiviral defense and autoimmunity : focus on type 1 diabetes
(2008-01-04)
Type 1 diabetes (T1D) is a disease characterized by the loss of insulin
producing beta-cells in the pancreatic islets of Langerhans. Interferons
(IFNs), produced by immune cells and infected parenchymal cells, may ...
Selenium cytotoxicity in cancer
(2013-05-20)
Selenium is an essential trace element, present in the 21st amino acid selenocysteine, which is specifically incorporated into selenoproteins. Today, there are 25 identified selenoproteins in humans, whereof many comprises ...