Search
Now showing items 1-5 of 5
Rapid detection of drug resistance and genetic characterisation of Mycobacterium tuberculosis isolates in Honduras
(2010-12-17)
Background: New challenges for tuberculosis (TB) control are emerging in the 21st century. The deadly combination TB/HIV as well as the development and spread of new forms of drug resistance are some examples. In this ...
Old receptors learn new tricks : biasing anti-IGF1R cancer therapy through the GPCR system
(2022-02-03)
As cancers progress, tumor cells exploit the extracellular signals generated from plasma membrane receptors for cell growth, migration, and anti-apoptosis. G protein-coupled receptors (GPCR) and receptor tyrosine kinases ...
Deciphering ret signalling in cell biology and development
(2015-05-27)
The rearranged during transformation (RET) tyrosine kinase regulates a plethora of
biological processes such as cell survival, proliferation and migration and is essential for the
normal development of several organs ...
New insights of LXR signalling in inhibition of cancer proliferation and inflammation
(2016-04-18)
Liver X receptors (LXRs) are ligand-activated transcription factors belonging to the nuclear receptor (NR) superfamily. Up-to-date, more than 1900 publications have established the role of LXRs in cholesterol homeostasis, ...
Regulation of mast cell function and survival in health and disease
(2016-11-16)
Mast cells are sentinels of danger but they are also the major effector cells in allergic disease causing the well-known allergic symptoms caused by their mediators such as histamine and prostaglandin D2 that are released ...