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Acute intermittent porphyria : studies of chronic disease, recombinant enzyme therapy and late complications
(2008-10-17)
This thesis comprise five studies on patients with acute intermittent porphyria (AIP) observed under different clinical conditions associated with the disorder. They have generally been monitored at the porphyria out-patient ...
The return of the nucleus : epigenetic regulation of autophagy
(2015-04-07)
Autophagy is an evolutionary conserved catabolic process activated in response to a variety
of cellular stresses, for example nutrient deprivation or chemotherapy. During autophagy,
cells engulf parts of their cytplasm ...
Role of antimicrobial peptides in tuberculosis and respiratory tract infections : clinical and mechanistic studies
(2015-10-14)
Antimicrobial peptides (AMPs) are effector molecules of the innate immune system in multicellular organisms. They are mainly expressed in epithelial cells and immune cells, providing the first line of defense against a ...