Search
Now showing items 1-3 of 3
The pathophysiology of respiratory chain dysfunction
(2005-02-18)
Mutations of mitochondrial DNA cause a variety of clinical syndromes. It is unclear whether impaired oxidative phosphorylation on its own is the main cause of pathology or whether other factors such as secondary metabolic ...
Hypothyroidism caused by a mutant thyroid hormone receptor alpha1 : consequences for development and physiology
(2008-01-11)
Lack of sufficient thyroid hormone during pregnancy and early postnatal
development results in profound mental retardation and motor deficits
whereas altered thyroid status in the adult is associated with disturbed
metabolic ...
Genetics of systemic autoimmunity and comorbidities
(2020-11-26)
Sjögren‘s syndrome (SS) is a systemic autoimmune disease that typically affects the salivary and lacrimal glands leading to dry eyes and dry mouth, but the patients may also have systemic involvement. Most patients with ...