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Studies on the mechanism of regulation of bile acid synthesis in humans with some aspects on genetic factors
(2005-10-28)
In the present investigation we studied human bile acid synthesis and its regulation both in vivo and in vitro and also evaluated a possible influence of polymorphisms in the CYP7A1 and CYP8B1 genes on bile acid synthesis ...
Wnt signaling in early brain development and disease
(2014-10-21)
Wnt/Planar Cell Polarity (PCP) signaling is involved in many cellular processes throughout the development of the embryo. These include control of proliferation, differentiation, migration and cell fate decisions. Deregulation ...
Microarray gene expression in immunological conditions
(2013-05-15)
The use of microarray techniques for gene expression analysis provides a global view of the transcriptional activity in a biological sample. In this thesis two conditions accompanied by disturbance in the immune system are ...