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Bacterial thioredoxin systems as potential drug targets in novel antimicrobial therapies
(2013-02-08)
Antimicrobial resistance is a big problem in modern medicine. One of the key components in the combat is the characterization of novel drug targets and the development of new classes of compounds targeting them. In the ...
Colorectal cancer : genome, transcriptone and proteome dynamics
(2005-05-27)
Colorectal carcinomas are the third most common malignancies in the
Western World. Despite screening programs about 70% of these tumors are
detected at advanced stages. Late diagnosis, however, results in a
significant ...
Development and biomedical applications of highly sensitive enzyme activity assays of thioredoxin, thioredoxin reductase and glutaredoxin
(2013-05-23)
Oxidative stress is implicated in the pathogenesis of many human diseases, thus it is interesting to study the relationship between antioxidants, the development and progression of diseases. The thioredoxin and glutaredoxin ...