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The effect of somatic disorders on brain aging and dementia : findings from population studies
(2009-05-13)
This doctoral thesis investigates the effect of somatic disorders on
dementia, Alzheimer s disease (AD) and brain aging in late-life. The data
for the studies are provided by the Kungsholmen Project (Studies I and
II) ...
Targeting chronic lymphocytic leukemia cells using anti-ROR1 monoclonal antibodies and small molecules inhibitors
(2015-04-29)
Chronic lymphocytic leukemia (CLL) is characterized by accumulation of malignant B cells in blood,
bone marrow, spleen and lymph nodes. It is the most common leukemia in the Western world. Major
progress has been made ...
Dynamic regulation of aryl hydrocarbon receptor function and activity by different stimuli
(2010-03-26)
Cells have to sense and adapt to changes in their surrounding environment. Most of the cellular responses to environmental and developmental stimuli are mediated by PAS (Per-ARNT-Sim) proteins. A member of this family of ...