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Detection and characterization of novel proteins in Trypanosoma cruzi
(2008-04-25)
Trypanosoma cruzi is a flagellated protozoan parasite. It infects a wide range of mammals, including humans. Human T. cruzi infections are endemic to South and Central America. The parasite is transmitted to humans mainly ...
Regulation of calcium flux by activating and inhibitory receptor crosstalk in NK cells
(2019-05-27)
The birth of a new born child kicks off the immune system to be on call and to respond promptly to threats from the environment. Natural Killer cells, classified as a member of the innate lymphoid cell family, express ...
Targeting chronic lymphocytic leukemia cells using anti-ROR1 monoclonal antibodies and small molecules inhibitors
(2015-04-29)
Chronic lymphocytic leukemia (CLL) is characterized by accumulation of malignant B cells in blood,
bone marrow, spleen and lymph nodes. It is the most common leukemia in the Western world. Major
progress has been made ...
Cancer therapy using viral and bacterial proteins as vectors for vaccines or as carriers of cytostatics
(2012-02-29)
New cancer therapies are urgently needed, since available treatment options today have negative side effects, and cure only about half of the patients with invasive cancer. One, relatively new, option is to vaccinate against ...