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Glucocorticoid administration : studies on weight regulation and metabolic implications
(2003-09-05)
Long-term treatment with glucocorticoids induces weight gain and increased risk to develop obesity-related metabolic complications like insulin resistance, type 2 diabetes and cardiovascular disease. Glucocorticoids have ...
Mechanisms influencing natural killer cell recognition of tumour cells
(2016-04-12)
Natural killer (NK) cells are part of our innate immune defence against virus-infected and transformed cells. Through a yet undefined mechanism, expression of inhibitory receptors for self-HLA class I molecules endow NK ...
Interactions between neuroblastoma and the immune system : cellular pathways and mediators
(2011-03-04)
Neuroblastoma (NB) is an embryonal tumor of early childhood arising in tissues of the sympathetic nervous system, such as the adrenal gland and paraspinal ganglia. It is the most common extra-cranial solid tumor of childhood, ...