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Molecular and morphological studies of folliculogenesis, oocyte maturation and embryogenesis in humans
(2008-05-22)
Infertility is a problem that affects about 15 percent of all couples.
Many can be helped by assisted reproductive techniques, but still today
many couples are treated without a successful outcome. The reason for
infertility ...
Chromatin remodeling and dna topology in transcription and genome stability
(2013-10-25)
Eukaryotic DNA is wrapped around histone proteins to form nucleosomes, the fundamental repeating unit of chromatin. DNA packaging into chromatin both solves and creates problems. It allows the centimeters, or even meters, ...
Mechanisms behind Smc5/6 transcriptional regulation and cohesin-mediated chromosome organisation
(2022-03-30)
The eukaryotic family of Structural Maintenance of Chromosomes (SMC) complexes are multi-subunit, ring-like protein complexes and include condensin, cohesin and the Smc5/6 complex (Smc5/6). Considered as an entity, this ...