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Chemokine receptor expression and function in experimental autoimmune neuroinflammation
(2007-05-25)
Neuroinflammatory lesions in the central nervous system (CNS) are characterized by the presence of leukocytes, mainly monocytes/macrophages, derived from the systemic compartment. We believe CC inflammatory chemokine ...
Characterisation of epitope-specific B cells and the role of IgG Fc sialylation in murine arthritis models
(2023-05-03)
Autoimmune diseases are a major burden for society and economy. One of the most common autoimmune diseases is rheumatoid arthritis (RA) characterized by joint inflammation, swelling and pain. If left untreated, it ultimately ...
Depression in youth and adults : etiology, outcomes, and comorbidities
(2022-02-02)
Depression is a common and debilitating mental disorder characterized by low mood, loss of interest in activities, and long-lasting functional impairment. It is a worldwide psychiatric illness with a wide range of ages of ...
Infection early in life and risk of non-affective psychosis
(2015-04-07)
In light of the increasing, but insufficient, evidence that various infections and immunological processes during brain development are associated with psychotic disorder, the aim of this thesis was to investigate infection ...