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Biosynthesis and biological role of leukotrienes in human lymphocytes
(2009-04-09)
Leukotrienes (LT) are biologically active metabolites of arachidonic acid. The key enzyme in leukotriene biosynthesis is 5-lipoxygenase (5-LO). Leukotriene B4 exerts its biological effect mainly via BLT1, the high affinity ...
Cost analysis and policy implications in psychiatric care
(2009-04-01)
The economic burden of mental health constitutes a substantial part of the total costs of illnesses. Most estimates of cost-of-illness focus on somatic illnesses and corresponding studies of mental health are few. In Sweden ...
Type 1 diabetes in pregnancy : perinatal outcome with special reference to fetal macrosomia
(2012-04-16)
The aim of this epidemiological study was to elucidate whether in recent years, obstetric and perinatal outcomes in pregnancies complicated by type 1 diabetes (T1DM) have improved or not. The objective was also to identify ...