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Regulation of gene transcription by the thyroid hormone receptors
(2006-05-26)
Thyroid hormone (TH) has important effects on postnatal development as well as on adult metabolic homeostasis. TH meditates its effects through different isoforms of the thyroid hormone receptors (TRs) encoded by the TRalpha ...
Quantitative evaluation of liver function using gadoxetic acid-enhanced MRI
(2022-04-29)
Before liver resection, a reliable and accurate assessment of the liver function is essential to ensure a safe surgery and avoid unfavorable complications such as post-hepatectomy liver failure (PHLF). Gadoxetic acid ...
Disturbances in myocardial diastolic and vascular function with the emphasis on type 2 diabetes : diagnostic and therapeutic opportunities
(2009-02-27)
Background and aims: Cardiovascular involvement is common in diabetes and diastolic myocardial and endothelial dysfunction are early signs. The prognosis is serious and tools for early detection and a search for improved ...
The effect of Plasmodium infection on cellular aging in humans
(2023-02-17)
Telomeres play an essential role in maintaining chromosomal integrity and stability. Telomere shortening is part of the natural aging process, nevertheless, accelerated telomere shortening has been linked to chronic diseases ...
Validation of biomarkers and digital image analysis in breast pathology
(2017-08-21)
For women worldwide, the risk of developing breast cancer is second only to that of nonmelanoma skin cancer. Significant improvements have been made in survival over the past decades and today about 80 % of the patients ...