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Exercise and outcome measures in patients with polymyositis and dermatomyositis
(2003-08-22)
Polymyositis (PM) and dermatomyositis (DM) are chronic idiopathic inflammatory myopathies (IIM) which are clinically characterized by symmetrical proximal muscle weakness, fatigue, myalgia and extra- muscular involvement. ...
Asthma in adolescents, during the transition from child to adult, effects on physiological parameters and health related quality of life
(2010-09-03)
The aims of this thesis were to evaluate physiological and allergic aspects and consequences of asthma and possible correlation between Health Related Quality of Life (HRQOL) and atopy, lung function, bronchial ...
Functional analysis of genes in the developing zebrafish pronephros and vasculature
(2009-08-21)
During glomerulogenesis, the recruitment and assembly of visceral epithelial cells (podocytes), endothelial capillary cells, and smooth muscle pericytes (mesangial cells) result in the formation of the glomerular tuft. The ...
Maternal antibody transfer in HIV-1 infected women and impact on infant health : the role of antiretroviral prophylaxis and breastfeeding practices
(2019-03-22)
Children born to human immunodeficiency virus type 1 (HIV-1) infected women are more vulnerable to infections and are more likely to die even when they are not HIV-1 infected. These adverse outcomes may blunt any gains ...
On the assessment of nerve involvement and of dysfunction in patients with spinal pain
(2009-01-23)
Nerve involvement originating in the spine can cause pain and/or organ dysfunction. Reliable and valid assessment of nerve involvement is a prime diagnostic task as it may require other than symptomatic treatment.
The ...
Regulation of p53 and susceptibility to cell death in chemically-induced preneoplastic hepatocytes
(2003-11-20)
Induction of preneoplastic lesions, termed enzyme-altered foci (EAF), is considered to be an early step in the development of liver cancer. In view of the relatively homogenous properties of the majority of EAF, these ...
Influence of oxidative stress on aryl hydrocarbon receptor signaling
(2013-05-13)
The aryl hydrocarbon receptor (AHR), a multifunctional protein and a key regulator of drug metabolizing enzymes, belongs to the basic-helix-loop-helix (bHLH)/PAS (Per-Arnt-Sim) super-family of transcription factors. The ...
Development of visual-motor coordination in children with neurological dysfunctions
(2013-03-15)
Graphomotor skills are complex perceptual-motor skills that are dependent upon the maturation and integration of a number of cognitive, perceptual and motor skills. They gradually develop through practice and instruction, ...
Epidemiological studies of epilepsy : incidence and risk factors
(2011-10-28)
Epilepsy is one of the most common serious neurological disorders leading to significant consequences for the affected. Despite the wealth of epidemiological data, there are still many un-answered questions. The major ...
Oral health and behavior in children with attention deficit hyperactivity disorder
(2007-04-20)
Attention deficit hyperactivity disorder (ADHD) is a common developmental
disorder and has a substantial impact on many situations in the child s
daily life. The present thesis investigates the behavior of children with
ADHD ...