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Exploring academic leadership in medical schools and universities in Iran
(2009-03-09)
Background: Medical education in Iran has been integrated into the health care system through a complex organizational change that included the formation of a single government division called the Ministry of Health and ...
Advances in exosome-mediated immunotherapy and diagnostics
(2018-03-28)
Exosomes are small vesicles with immune-stimulatory capacity, which can activate T cell responses in a B cell dependent manner, and therefore may serve as immune therapeutic tools. Peptide-loaded dendritic cell (DC)-derived ...
On age related changes in axons and glia of the central nervous system
(2002-08-09)
A growing body of evidence shows that phenotypic changes including axon aberrations, rather than loss of neurons, account for behavioral impairments during aging. The present thesis was undertaken to investigate the ...
Epigenic regulation and posttranslational modification of human cytochrome P450s : focus on CYP2W1, CYP1A2 and CYP2C18
(2008-11-21)
The cytochrome P450 superfamily represents a very important group of
enzymes that are responsible for the metabolism of drugs as well as of
endogenous compounds. Many P450s are genetically polymorphic causing
important ...
Extracellular vesicles : mediators of immune modulation in the lung and as therapeutic vehicles
(2018-09-18)
Extracellular vesicles (EVs) are released from all cell types, and carry a wide setup of proteins, nucleic acids, lipids and other cargo. The overall aim of this thesis is to explore EV-based immune therapy, but also to ...
Eicosanoids and exosomes : a link between macrophages and lung cancer
(2017-11-01)
Chronic inflammation increases the risk of lung cancer. Macrophages (MO) are important players in inflammation, with regulatory and executive functions. Eicosanoids and exosomes can be both triggers and mediators of these ...
Analysis of extracellular vesicles and their application in immunotherapy
(2021-09-28)
Extracellular Vesicles (EVs) are nano-sized particles secreted by most, if not all, cell types. They are important mediators in intercellular communication and carry a broad array of biomolecules such as lipids, nucleic ...