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Cardiovascular disease among professional drivers and subway staff in Stockholm
(2007-03-30)
Professional drivers are at an increased risk of myocardial infarction (MI), but the underlying causes are not clear. The aims of this thesis were to broaden our understanding of the causal factors involved in this elevated ...
Clinical and genetic stratification of childhood psoriasis
(2015-04-29)
Psoriasis is a clinically heterogeneous and common disease affecting about 2-3% of the
population in Sweden. Twin and family studies have shown a strong and complex genetic
background in psoriasis. The strongest known ...
Clinical aspects on glucose-lowering therapies in type 2 diabetes
(2012-09-03)
Type 2 diabetes is a progressive disease with deterioration of glycaemic control over time in association with loss of endogenous insulin secretion. As a consequence of this, sulphonylureas (SU), which exert their mode of ...
Characterizing cancer cell signaling at the protein level : from targeted to proteome and phosphoproteome‐wide analyses
(2017-09-11)
Proteins are the effectors of cellular functions and the constituting elements of cellular signaling cascades. The ability to analyze the abundances and the dynamics of proteins is central to dissect cellular signaling and ...