Search
Now showing items 1-10 of 14
Functional studies on the nuclear receptor Nurr1
(2004-04-28)
The nuclear receptor (NR) superfamily comprises the largest family of ligand-activated transcription factors in eukaryotes, and it plays critical roles in many aspects of vertebrate development and physiology. The NR family ...
Indicators of apoptosis and proliferation in haematological malignancies : with special reference to drug resistance and prognosis
(2001-09-07)
Successful treatment of acute myeloid leukaemia (AML) and high-grade
non-Hodgkin's lymphoma (HG- NHL) is hampered by development of drug
resistance. A better understanding of mechanisms responsible for drug
resistance ...
Glucocorticoid receptor cross-talk with NF-kappaB and AP-1 : functional role and mechanisms
(2005-03-18)
The protein investigated in this thesis is the glucocorticoid receptor (GR), which is a ligand activated transcription factor that belongs to the superfamily of nuclear hormone receptors. The GR contains three functional ...
Aspects on chronic stress and glucose metabolism in women with recurrent vulvovaginal candidiasis and in women with localized provoked vulvodynia
(2007-04-06)
Objective: To evaluate the degree of stress in women with recurrent vulvovaginal candidiasis (RVVC) and in women with localized provoked vulvodynia (LPV) (former vulvar vestibulitis syndrome) compared with controls. To ...
Linkage and association analysis in multiple sclerosis
(2001-09-03)
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which is characterized by relapsing or progressive demyelinating plaques in the brain and spinal cord. It is well established that ...
The functional impact of gut microbiota on CNS regulation of local and systemic homeostasis
(2018-08-24)
The “gut microbiota” is widely accepted as an integral part of the gut homeostasis, and is thought to contribute to the establishment of intestinal barrier. Growing body of research suggest that the influence of gut ...
Epidemiological studies of medication use and effectiveness in bipolar disorder
(2017-09-19)
In the last decades, new treatments for bipolar disorder (BD) have emerged, prompting a decrease in the use of lithium – the former “gold standard” for relapse prevention, and increasing the possibilities for individualized ...
Lumbopelvic pain during and after pregnancy : aspects of catastrophizing, fear-avoidance beliefs, physical ability and health-related quality of life
(2010-05-07)
Background: Every second pregnant woman suffers from lumbopelvic pain,
and many report remaining pain postpartum. Lumbopelvic pain affects the
woman s life in many ways and it is the main reason for sick leave ...
Enhancing survival of mothers and their newborns in Tanzania
(2005-05-06)
General aims: The main purpose of the present studies was to examine the problem of maternal and perinatal mortality in an upcountry region of a low-income country. This was done by estimating the magnitude of maternal and ...
Epidemiological and clinical aspects of fertility and diseases associated with infertility among Swedish-born and foreign-born women
(2007-05-18)
Objective: To examine the association between sociodemographic factors and first birth country of birth and hospitalization for pelvic inflammatory disease (PID), ectopic pregnancy (EP), infertility trends in Sweden during ...