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The effects of hand training in patients with Welander distal myopathy and myotonic dystrophy type 1
(2009-05-19)
The overall aim was to study and gain knowledge about the effects of hand
training on both functional capacity such as hand function and Activities
of Daily Living (ADL) in patients with Welander distal myopathy (WDM) ...
Molecular characterization of Mycobacterium tuberculosis complex from Kampala, Uganda
(2008-11-27)
Uganda is one of the countries with the highest burden of tuberculosis (TB) in Sub-Saharan Africa, ranked 16th among the 22 high-burden countries in the world. Poor peri-urban areas of developing countries with inadequate ...
Risk characterization of familial cancer using the Swedish family-cancer database with a special reference to breast cancer
(2003-11-07)
This thesis reports on epidemiological studies on family related cancer in Sweden. The Family-Cancer Database was constructed in 1996 from several national registries. Family relations were available from the Generation ...
Molecular characterization of Mycobacterium tuberculosis complex isolates from Sweden
(2010-04-21)
Tuberculosis (TB), caused by the Mycobacterium tuberculosis complex
(MTC), is a serious infection in man and animals. According to the World
Health Organisation (WHO), about one third of the world´s population is
infected ...
Two novel combination therapies of glioblastoma multiforme from a Cx43 perspective : studies of in vitro models
(2008-03-28)
The group of patients suffering from the malignant brain tumour
glioblastoma multiforme (GBM) have a median survival of only about one
year. Thus, new treatment strategies are urgently needed.
Gap junctions are ...
PET studies of the serotonin system in major depression and its treatment
(2014-10-03)
The serotonin system has been implicated in major depression since the
1960s, mainly based on the serotonin enhancing properties of
antidepressants. Positron emission tomography, PET, is the in vivo
molecular imaging ...
PET studies of the serotonin transporter in the human brain
(2006-10-27)
The serotonin (5-HT) system attracts considerable attention in research on the pathophysiology and drug treatment of neuropsychiatric disorders. The brain imaging technique Positron Emission Tomography (PET) allows for ...
Self-rated health : biobehavioral determinants with focus on inflammatory factors
(2010-05-28)
Self-rated (subjective) health is an independent predictor of future
mortality, but neither the mechanisms behind this relation nor the
biological determinants of poor self-rated health are known. Inflammatory
cytokines ...
Prevention of liver cancer in chronic liver disease : an experimental study of sodium selenite and rat hepatocarcinogenesis
(2011-11-21)
Selenium treatment in supranutritional but subtoxic doses has previously been shown to inhibit cell proliferation in preneoplastic lesions in a rat liver carcinogenesis model. The mechanisms are not known, but thioredoxin ...
Human papillomavirus infection in healthy youth and in hypopharyngeal cancer
(2016-04-22)
The aim of this thesis was to follow the prevalence of human papillomavirus in the oral cavity and in the cervix in youth during the period of 2008-2015, a period when HPV vaccination was gradually introduced to young girls ...