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Studies on coactosin-like protein interaction with 5-lipoxygenase
(2009-10-16)
Leukotrienes (LTs) are proinflammatory lipid mediators derived from polyunsaturated arachidonic acid, which is ester-bound at the sn-2 position of glycerol in cellular phospholipid bilayers. In LTs biosynthesis, 5-lipoxygenase ...
Sequestration, virulence, and future interventions in Plasmodium falciparum malaria
(2005-11-11)
The Plasmodium falciparum infected erythrocyte (iRBC) withdraws from the peripheral circulation to hide in the deep microvasculature during maturation. This phenomena, referred to as sequestration, is believed to cause ...
Development of a recombinant protein vaccine against Plasmodium falciparum malaria
(2006-05-26)
Malaria, caused by Plasmodium falciparum is one of the world´s deadliest diseases, killing one to two million children, while another 500 million suffer from clinical attacks every year. Infections caused by P. falciparum ...