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On the fate of triclosan in humans
(2009-05-22)
Triclosan is a chlorinated organic compound which, due to its antibacterial properties in vitro, has found widespread use in a variety of products such as textiles, plastics and healthcare products. Humans are directly and ...
Modulating the activity of OGG1 using small molecules to target the oxidative DNA damage response in cancer and inflammation
(2021-10-05)
The production of reactive oxygen species (ROS) is increased in several pathological conditions including cancer and inflammation. Multiple lines of evidence suggest that ROS are involved in signaling events that promote ...
Strategies for modulation of dendritic cell responses
(2012-05-10)
With increased knowledge in dendritic cell (DC) biology, innate immune receptors and their ligands, and the shaping of adaptive responses, refined approaches to modulate our immune system are today emerging as treatment ...