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Intelligence and cardiovascular health : epidemiological studies of swedish men
(2010-08-20)
Aim: A first aim of this thesis was to examine the relationship between intelligence in early adulthood and health outcomes, mainly cardiovascular morbidity and mortality, CVD, later in life using register-based data on ...
The role of telomerase reverse transcriptase in human malignancies : genetic polymorphisms and promoter mutations
(2017-09-15)
Telomerase is a ribonucleoprotein with its catalytic subunit telomerase reverse transcriptase (TERT) as a key component, lengthening telomeres. In differentiated human cells, telomerase is silent due to the transcriptional ...
Telomeres and telomerase and their functional applications in myeloproliferative neoplasms and acute myeloid leukemia
(2016-10-25)
Myeloproliferative neoplasms (MPNs) are a group of diseases characterized by hyperproliferation in the myeloid lineages of the bone marrow, leading to increased levels of circulating mature blood cells from one or more ...
Cardiac function in experimental septic and non-septic conditions with special reference to the endothelin system
(2006-11-03)
Myocardial depression in sepsis has been intensely investigated for the past 30 years and still poses a considerable issue in the intensive care units. Both systolic and diastolic dysfunction is implicated, correlating ...